| abstract |
The present invention discloses a peptide derivative of general formula (I) or its pharmaceutically acceptable salt and hydrate with the following structure: Wherein R 1 is a saturated heteroatom group, or a saturated or unsaturated heterocyclic group; R 2 and R 3 are independently selected from a hydrogen atom or a functional group; X is O, -S-, -S(=O )-, -SO 2 - or P; R 4 is a saturated or unsaturated heteroatom group, or a saturated or unsaturated heterocyclic group; a is 0-4, b is 0-4, c is 0-4, d is 0-4, k is 0-1. The invention provides a series of peptide derivatives for antiviral research. |