http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102746359-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 |
filingDate | 2012-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102746359-B |
titleOfInvention | A kind of synthetic method being prepared ursodesoxycholic acid by Chenodiol |
abstract | The present invention relates to a kind of novel method being prepared ursodesoxycholic acid by Chenodiol; take Chenodiol as raw material; respectively by after carboxy protective and after the selective protection of 3-hydroxyl; again by 7-position hydroxyl through Mitsunobu reaction or adopt Tosyl chloride, methylsulfonyl chloride, 4-Nitrobenzenesulfonyl chloride make ester, then slough protecting group and prepare ursodesoxycholic acid.The present invention is compared with other technique, and it has reaction conditions gentleness, simple to operate, and efficiently, yield is high, optical purity high, has wide industrial production prospect. |
priorityDate | 2012-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.