http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102744022-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b45e0e78fe049a56c38f6da934012462 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N25-28 |
filingDate | 2012-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa708cc4143200e6fb8cb51f0b6a92f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fff899f0fd1b29ecf0323c10159b5ac4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba2f9dba27324909beba4e1d6375cd8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aae5df762e55635f43f27c6626dc00e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3d0a49bc5aed5d6fb30db74b08becde |
publicationDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102744022-B |
titleOfInvention | Hollow microcapsule, acidic or alkaline controlled-release microcapsule and preparation methods thereof |
abstract | The invention relates to a hollow microcapsule, an acidic or alkaline controlled-release microcapsule and preparation methods thereof, belonging to the field of biological agents. The preparation method of the hollow microcapsule comprises the following steps of: preparing a microcapsule through a layer-by-layer self-assembly method by taking calcium carbonate as a core and selecting polyelectrolyte cation and anion with opposite charges under a preparation condition; and then removing the core to obtain the hollow microcapsule. The wall of the hollow microcapsule is formed by alternating PAH/PSS (Polypropylene Amine hydrochloride/Poly Sodium Styrenesulfonate), and the hollow microcapsule can loaded with Cry protoxins of bacillus thuringiensis insecticidal crystal proteins under an acidic condition so as to obtain a microcapsule dosage form with release controlled under an alkaline condition. The microcapsule dosage form keeps the insecticidal activity of the cry protoxins, can assist the cry protoxins to resist the influence of certain environmental factors, also enables the insecticidal proteins to be specifically released in an alkaline environment of an insect midgut and keep stable in a general environment and plays an important role in the actual application of the Bt (Bacillus thuringiensis) insecticidal proteins on pest control. |
priorityDate | 2012-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.