| abstract |
The invention provides a kit for detecting high myopia, comprising an optional reagent for detecting the mutations of one or more loci of 1901, 2156, 2180, 2238, 4138, and 4718 of ZNF644 gene. The invention further provides an application of the mutations of one or more loci of 1901, 2156, 2180, 2238, 4138, and 4718 of ZNF644 gene in preparing a reagent for detecting high myopia. The kit provided by the invention can predict the susceptibility of a sample to be detected to high myopia, can be used for early monitoring and detecting high-risk population of high myopia, and can be used for carrying out early prevention and treatment to reduce visual loss. |