http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102731786-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G75-045 |
| filingDate | 2012-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c983dba73b66e5a253540af2f940b54e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_619194882d5447ef3b39772881458f64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e7d59480fd80b2fadde3a1806fe0ebf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8664c8b173c4ca90959d787d76c68e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c370933a43112a2f7c7971c7a2e4e8ee |
| publicationDate | 2014-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102731786-B |
| titleOfInvention | Method for controllably preparing polymer gel particles through non-aqueous emulsion polymerization system |
| abstract | The present invention discloses a method for controllably preparing polymer gel particles through a non-aqueous emulsion polymerization system. The method comprises the following steps: (1) dissolving an emulsifier in a non-polar solvent, and adding a multi-double bond functional group monomer to the resulting solution in a dropwise manner after dissolving; dissolving a dual-mercapto functional group monomer in a polar solvent, adding the resulting solution to the solution containing the multi-double bond functional group monomer in a dropwise manner, adding triethylamine in a dropwise manner, and carrying out a reaction under magnetic stirring; and (2) adding a polar solvent, carrying out layering with a tap funnel, evaporating the solvent, carrying out open-air drying, and carrying out vacuum drying to obtain the polymer gel particles with a average particle size of 210-623 nm. With the present invention, a non-aqueous emulsion polymerization method is adopted, and the dispersed phase and the continuous phase are the organic solvents, such that the polymer gel particles can be controllably prepared, and the interference on the polymerization reaction due to water can be avoided; the prepared emulsion has characteristics of narrow average particle size distribution, controllable particle size, easily-controllable reaction process, and the like; the resulting polymer has multi-functional groups, wherein the multi-functional groups can be further modified, and are provided for loading and releasing drugs, such that the polymer can be adopted as the platform for design of a wide variety of gel drug release systems. |
| priorityDate | 2012-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.