http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102731542-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a99a0e1a23aa8a70dbef98cab6fa854d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 |
| filingDate | 2012-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e5990116578cb5a877137db9ea09e91 |
| publicationDate | 2012-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102731542-A |
| titleOfInvention | A kind of preparation method of p-bromophenylboronic acid |
| abstract | The invention discloses a preparation method of p-bromophenylboronic acid. The method comprises: mixing p-dibromobenzene and boric acid triester according to the molar ratio of 1:1 to 1:5, and then dissolving them in an organic solvent to prepare the mixture , add n-butyllithium hexane solution to the mixture at -60~0°C, after the reaction is complete, post-treat the resulting reaction solution to obtain p-bromophenylboronic acid; the mass dosage of the organic solvent is the mass of p-dibromobenzene 6~20 times of 6~20 times, the consumption of described n-butyl lithium hexane solution is based on n-butyl lithium molar weight, and the ratio of described n-butyl lithium and p-dibromobenzene molar weight is 1~2:1; The present invention The ideal reaction temperature is -40~-30°C, and the substantial increase in the reaction temperature makes the process of the present invention easier to realize industrial production. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106008576-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103030660-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106117255-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108484653-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108484653-A |
| priorityDate | 2012-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.