http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102727521-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d97e4917a5bb4e1e431ab259566c21b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-12 |
| filingDate | 2012-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a797b06a7f808f7a611096ace7a4f06 |
| publicationDate | 2013-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102727521-B |
| titleOfInvention | Preparation method of gentamycin bismuth carbonate capsule content intestinal release pellets |
| abstract | The invention discloses a preparation method of gentamycin bismuth carbonate capsule content intestinal release pellets, comprising the following steps: uniformly mixing gentamycin sulfate and basic bismuth carbonate, adding cross linked sodium carboxymethyl cellulose, sodium carboxymethyl starch, and starch paste, preparing particles, drying, putting in a sugar-coat pot, coating the particles with spraying powdered steatile by using a carboxymethylcellulose sodium solution to let the particles be smooth and have no edges and corners, conducting granulation to obtain raw medicine based nucleuses; fully dissolving cellulose acetate-phthalate, diethyl phthalate, and Tween 80 with ethanol to obtain an enteric coating solution; putting the raw medicine based nucleuses in the sugar-coat pot, coating the enteric coating solution on the based nucleuses by spraying, conducting vacuum pumping, conducting air drying to obtain the gentamycin bismuth carbonate intestinal release pellets. According to the invention, the prepared pellets have good fluidity, low weight variation in capsule filling process, and easiness in filling; by spraying the enteric coating on the based nucleuses, the preparation can direct lesions through gastral cavity to directly affect enteric cavity, and has good curative effect. |
| priorityDate | 2012-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.