Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_951ade9cb9f29eb8a29ddae1e2fc87e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc905cbef116a1ec61d12125af9427f3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6911 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 |
filingDate |
2010-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d9455aac194cb9084f423bf688bbed6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edac9fca373d63796efde3eb1160c400 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae9e96d573658e74668f053a70be6fa9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17b522c41e310b79aa4008a74003c804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1174b15e83e88f0cd88b8d8798a0656e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e365efad4447c6e1e8a3aebae1dd1416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49dc040d80423a33209035b5849f8e2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0c0991fc3a935c7380a7f3235863e1f |
publicationDate |
2014-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-102724966-B |
titleOfInvention |
Target-aiming drug delivery system for diagnosis and treatment of cancer containing liposome labeled with peptides which specifically targets interleukin-4 receptors, and manufacturing method thereof |
abstract |
The present invention relates to a target-aiming drug delivery system for diagnosis and treatment of cancer containing liposome labeled with peptides which specifically targets interleukin-4 receptors, and a manufacturing method thereof. The liposome which contains anticancer drugs labeled with IL4RPep peptides prepared in accordance with the present invention can deliver drugs to cancer cells in which IL-4 receptors are overexpressed by IL4RPep peptides which specifically bind to IL-4 receptors, and the drug delivery can recognize cancer cells specifically by a label. Thus, IL4RPep peptides can increase the effect of drugs only on cancer tissues and at the same time significantly reduce the side effects on normal tissues, which makes possible in vivo (molecular) imaging and early diagnosis of tumors.; Therefore, the liposome which contains anticancer drugs labeled with IL4RPep peptides of the present invention can be applied, as the target-aiming drug delivery system, effectively to the diagnosis and treatment of cancers. |
priorityDate |
2009-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |