http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102719378-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb351a5a4e03ee3773bd0df5dbae9ac3 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-10 |
| filingDate | 2012-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3907a8fd544a5da0cc8d36516e3e2dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7389816de3554c597ab250b448a0731 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33994432ac2f0f50b598fe9ae5305345 |
| publicationDate | 2013-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102719378-B |
| titleOfInvention | Method for preparing (-) gamma-lactam by catalysis asymmetry of microorganism |
| abstract | The invention discloses a method for preparing (-) gamma-lactam by the catalysis asymmetry of microorganism, belonging to the technical field of biological engineering. Racemic modification 2-aza-second ring-(2.2.1)-heptane-5-alkene-3-ketone is hereafter referred as (+/-) gamma-lactam. The method disclosed by the invention comprises the following steps of: screening from soil to obtain a microorganism bacterial strain having high-enantioselectivity (+) gamma-lactam, identifying to be Delftiasp, wherein the preservation No. is CGMCCNo.5755; and hydrolyzing (+/-) gamma-lactam in a water phase system in a stereoselectivity way, to prepare the (-) gamma-lactam. Under the condition that the concentration of substrate is 200g/L, the (-) gamma-lactam is extracted, concentrated in an evaporating way, and crystallized in a cooling way to obtain the (-) gamma-lactam, wherein the optical purity of the (-) gamma-lactam is 95.0%-99.9%, and the chemical purity of the (-) gamma-lactam is 95%-99%. The method for preparing the (-) gamma-lactam by the catalysis asymmetry of the microorganism has the characteristics of being high in stereoselectivity, high in reaction yield and high in product concentration. |
| priorityDate | 2012-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.