http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102718818-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53b3048adafe2988c6f0df1ffb53012d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-706 |
| filingDate | 2012-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abcb3de905edc64860beb76d914507d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11076ce40e603388ed70df51be249cac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c2fe67390f9d5b81fee15a26d506e62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f13c97780d8a198ac10a153e4a1c2021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_100a1f3d3ed5476b3ef8eaf891004a26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6ed3609fb1b4ef3137a34fe958568f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51e960891e0763d8433e0bdf77dc34bc |
| publicationDate | 2014-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102718818-B |
| titleOfInvention | Nitrogenous troxerutin derivative, preparation method thereof and application |
| abstract | The invention discloses a nitrogenous troxerutin derivative and a preparation method thereof, and belongs to the field of medicinal chemistry. In the method, troxerutin and divinyl ester are used as raw materials, organic solvents serve as reaction media under catalysis of hydrolytic enzyme, the reaction temperature ranges from 40 DEG C to 60 DEG C, troxerutin vinyl ester is obtained and serves as a substrate respectively reacting with dimethyldiguanide or piperazine compounds under enzyme catalysis, troxerutin derivatives containing triazine rings and piperazine rings are respectively obtained, and the compounds have antitumor activity. The preparation method is moderate in reaction condition and simple in operation, the enzyme can be recycled, and a good way is provided for nitrogenous derivatization of natural products. |
| priorityDate | 2012-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 126.