http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102716080-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41e7550911d3e588caa3fbc6a252ad80 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 |
filingDate | 2012-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3c49a531d4151785e6ddd7824684889 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_302f197af20b9dd6490beaa549ca86ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_397196419ede886b7d3d86c6090e5998 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_391036a82c4f1d92f69813cef7856df9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3a659f3d1d2e9e77f238dca2b5d5277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e39647a260d36c1f768cabf95eaaa196 |
publicationDate | 2014-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102716080-B |
titleOfInvention | Suspension containing andrographolide solid lipid nanoparticles as well as preparation method and application of suspension |
abstract | The invention relates to suspension containing andrographolide solid lipid nanoparticles as well as a preparation method and an application of the suspension, wherein the andrographolide solid lipid nanoparticles are dispersed in emulsion formed by purified water and emulsifying agents and consists of andrographolide and lipid materials, the weight ratio of the andrographolide to the lipid materials to the emulsifying agents is (1-15): (35-70):(20-50), and the consumption of the purified water is metered according to the principle that 1ml of purified water is added into 5 to 20mg of emulsifying agents. The suspension has the advantages that the andrographolide is covered and sealed in lipid inner cores of the solid lipid nanoparticles, the in-vivo absorption of the medicine is improved, the bioavailability is improved, meanwhile, and the slow release performance and the targeting performance are realized, so the toxic or side effect is reduced, and the anti-tumor curative effect is improved. |
priorityDate | 2012-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.