abstract |
The present invention provides immunologic opsonin to identify the humanized antibody of RGD sequence.The biological function of some suppression RGD albumen in these antibody, thus the therapeutic effect to the various disorderly or disease related to RGD albumen for the display, the described disorder related to RGD or disease include growth and the transfer of cancer such as cancerous cell, and inflammatory diseasess such as rheumatic arthritis, osteoarthritis, hepatitis, endometriosis, bronchial asthma, fiber-like change, diabetes, arteriosclerosis, multiple sclerosis, granuloma, inflammatory bowel disease (ulcerative colitiss and Crohn disease) and autoimmune disease etc.. |