abstract |
The present invention relates to the chitosan derivatives of water soluble quaternary ammonium, it is formed for the protection of the hydrogel matrix with extensive germ resistance with coating medical devices.In order to realize the formation of hydrogel, quaternised chitosan can with polymerizable groups, particularly as the photocrosslinking reaction group grafting of methacrylic ester, PEG derivative, and by heat or UV polymerization process convert hydrogel to.Hydrogel is the aquation crosslinking polymerization system forming pad bucker, and it comprises the water of beinthebalancestate.The present invention is widely used for many medical facilities biological example medical facilities as in contact lens, bioimplant.The invention describes based on the formation of the novel hydrogels of the quaternised chitosan derivatives of photocrosslinking reaction group grafting, thus be provided as the hydrogel of antibacterial waterproof coated agent. |