| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16abbdd45696352c4d952706a85fd7af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a08a12441d855b8949d9ac954638567b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate |
2010-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_446fac58bead92411a92e61e6b62b9f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59e4a3857da01208d7b4392bf8bbc7bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c6ee6657d1d6bc78bb73806c7a37fca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e123e3938180b198edfe39cbc2c1fc7a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2738fc0bb1ca03ea17c0dcb118f2dbe4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_121a4c53c344c10be653ea832ddeaa33 |
| publicationDate |
2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-102711777-B |
| titleOfInvention |
Tissue-regeneration promoter using recruitment of bone marrow mesenchymal stem cells and/or pluripotent stem cells in blood |
| abstract |
Intravenous administration of HMGB-1 and S100A8 was found to cause recruitment of bone-marrow-derived cells to a skin ulceration site and promote healing of the skin ulceration. Also, bone-marrow-derived cells expressing nerve cell markers were found in the brains of stroke model mice administered HMGB-1 intravenously after stroke inducement. In comparison with controls, mice administered HMGB-1 intravenously exhibited pronounced improvement in terms of stroke lesion contraction. Mice administered HMGB-1 intravenously had a higher post-stroke survival rate. Using mice, the involvement of bone-marrow pluripotent stem cells in the bone-fracture healing process was confirmed, which indicates that bone-marrow-derived cells far from the injury site moved to the bone-fracture area to repair injured tissue. |
| priorityDate |
2009-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |