http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102702514-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7410cde60f2e3e9954355e4a2d7d4174 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F6-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G69-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L29-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L29-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G69-44 |
filingDate | 2012-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae8465a76f73f62466890f0e2c88ddca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e777297096efd6a9ad9f40e7363dbd13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_034f67f97d147dad1bb251bc71690511 |
publicationDate | 2014-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102702514-B |
titleOfInvention | Multi-block copolymer of polyester amide and aniline oligomer and preparation method thereof |
abstract | The invention belongs to the technical field of biomedical polymer materials and particularly relates to a multi-block copolymer of polyester amide and an aniline oligomer and a preparation method thereof. Natural alpha-amino acid, aliphatic diol, diacid (or diacyl chloride) and a bis-amino capped aniline oligomer are taken as raw materials, and the reparation method comprises the following steps: firstly, synthesizing diol diamino acid ester p-toluene sulfonate (a nucleophilic monomer) and diacid p-nitrophenol ester (an electrophilic monomer); and in the polycondensation process of a solution, preparing an irregular or alternate multi-block copolymer of the polyester amide and the aniline oligomer by changing the molar ratio of the two monomers as well as the adding sequence of the aniline oligomer. The prepared copolymer is a biodegradable material with electrically activity; physical and chemical properties of the copolymer can be effectively regulated by changing chemical structures of the monomers and the aniline oligomer; and as an ideal tissue engineering material, the multi-block copolymer is particularly applicable to preparation of a nerve conduit. |
priorityDate | 2012-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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