http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102702297-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00
filingDate 2012-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fc03cda927261c53bcfba60ed819872
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2632e1797068c325cbb6dbe08084b4ea
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publicationDate 2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102702297-B
titleOfInvention Preparation method of cholic acid-naphthalimide compound
abstract The invention discloses a preparation method of a cholic acid-naphthalimide anti-tumor lead compound, belongs to the field of chemical synthesis of medicaments, and particularly relates to a synthesis method of a new naphthalimide compound with a chemical structural general formula shown in the specification. The preparation method of the compound is economical, simple, mild and effective. The obtained compound has extremely high inhibitory activity on HepG2 cells; and compared with phase-II clinic lead compound methylamphetamine, the compound partially has more superior inhibitory activity and can be used for preparing anti-tumor medicaments.
priorityDate 2012-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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