| abstract |
The invention discloses a 4-(3-chloro-4-methoxylanilino)-6-(3-amidophenyl)quinazoline compound shown as a structure formula (I). In the structure formula (I), R is any one of -H, -COCH3, -COCF3, -COCH=CHCOOH, -COCH2Cl, -COCCl3, -COCH=CH2, -COC(CH3)3, -COCH2CH3 and -COHBrCH3. The invention further relates to a preparation method of the compound, a pharmaceutically-acceptable salt of the compound, and applications of the compound and the pharmaceutically-acceptable salt thereof to preparation of an antitumor medicament. |