| abstract |
The invention relates to a benzenesulfonamide compound and application thereof. The benzenesulfonamide compound is a compound shown as a formula I or pharmaceutically acceptable salt thereof and can be used as a carbonic anhydrase IX inhibitor. In the formula I, R1 to R10 are independently selected from hydrogen, C1 to C6 straight-chain or branched-chain alkyl, C1 to C6 straight-chain or branched-chain alkoxy, amino and halogen, and halogenated straight-chain or branched-chain C1 to C6 alkyl or sulfamide, at least one of R1 to R10 is the sulfamide, X is NH, O or S, and n is 0 or 1. |