| abstract |
Present invention is disclosed the pharmaceutical carrier of the slow-release of a kind of performance improvement, this pharmaceutical carrier comprises (a) a kind of inside and outside fusing point aliphatic additive higher than temperature 37 DEG C；(b) a kind of water-soluble, low viscous and non-irritating additive granules；(c) a kind of water-swellable, water-insoluble acidity (or alkalescence) polymer；(d) a kind of alkalescence (or acid) material；(e) a kind of water soluble surfactant active；(f) a kind of medicine.This pharmaceutical carrier has more preferable drug release feature, higher anti-" salt poisoning " effect, has more preferable release homogeneity, preferably alleviates or solve " end release " problem；There is lower mucous membrane irritation, more preferable biocompatibility；It is difficult to occur that burst drug release dosage in other words inclines and the drug safety problem such as releases. |