http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102697742-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e2d17db066c8dce859c3322182d2af4
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19
filingDate 2012-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0309b17a9993629523858770f670ee0d
publicationDate 2013-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102697742-B
titleOfInvention Preparation process of cefozopran hydrochloride for injection
abstract The invention relates to cefozopran, in particular to a preparation process of cefozopran hydrochloride for injection. After processing through the preparation process, the problem that the cefozopran hydrochloride is difficultly dissolved in water, is unstable and is easily degraded especially in the presence of alkaline matter is solved. By means of a lot of experiments, the inventor finds out that temperature control and pH control are key factors, and dissolubility and stability of the cefozopran hydrochloride are greatly improved by controlling the temperature and the pH. After the processing through the preparation process, the appearance and the water content of the obtained product accord with the provision, and relative matter detected by the obtained product also accords with the provision.
priorityDate 2012-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 33.