http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102686599-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 |
| filingDate | 2010-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102686599-B |
| titleOfInvention | The Phosphoramidate derivatives of nucleosides |
| abstract | Present invention offer can be used for preventing or treat the compound of formula I of HCV infection or its pharmaceutically acceptable salt or solvate, including its any possible stereoisomer, wherein: R 1 It is hydrogen, C (=O) R 6 Or C (=O) CHR 7 ‑NH 2 ；R 2 It is hydrogen；Or C 1 ‑C 6 Alkyl or phenyl, both are optionally each independently selected from halo, C by the 1st, 2 or 3 1 ‑C 6 Alkyl, C 2 ‑C 6 Alkenyl and C 1 ‑C 6 The substituent of alkoxyl, hydroxyl and amino replaces, or R 2 It is naphthyl；Or R 2 It is indyl；R 3 It is hydrogen, C 1 ‑C 6 Alkyl, benzyl；R 4 It is hydrogen, C 1 ‑C 6 Alkyl, benzyl；Or R 3 And R 4 Connected carbon atom forms C together 3 ‑C 7 Cycloalkyl；R 5 It is C 1 ‑C 10 Alkyl, C 3 ‑C 7 Cycloalkyl, benzyl or phenyl, its any one be optionally each independently selected from hydroxyl, C by the 1st, 2 or 3 1 ‑C 6 Alkoxyl, amino, one or two C 1 ‑C 6 The substituent of alkyl amino replaces；R 6 It is C 1 ‑C 6 Alkyl；R 7 It is C 1 ‑C 6 Alkyl；R 8 It is hydrogen or halogen. |
| priorityDate | 2009-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 193.