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publicationDate 2012-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102675355-A
titleOfInvention Preparation of antiviral drug [1S-(1α, 3α, 4β)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl] -6H-purin-6-one method
abstract A method for preparing the antiviral drug entecavir is disclosed. A resin adsorption method for separating and purifying entecavir is also disclosed. In addition, various intermediates for the preparation of entecavir are also disclosed.
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