http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102675280-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_38f6403d850a1fe9e34ef7fd5a010318 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d29a918d7ec83cea80d61d1dbc478cf |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 |
| filingDate | 2011-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62695b57d98fc2099b2a43eb2371e37f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34614a7ba9241455c1d69d065558a2bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01304b7330cd9f165a409be6325cb77c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4af8ca89b637be9939a1bf44a76e50bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c670cb4803ea9f695ea87a34dbc38fc1 |
| publicationDate | 2015-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102675280-B |
| titleOfInvention | Trifluoromethyl-containing indole ketone compound,and preparation method and application thereof |
| abstract | The invention discloses a trifluoromethyl-containing indole ketone compound, and a preparation method and application thereof. The compound has the chemical structural general formula I, wherein Y is carbon or oxygen; or the compound has the chemical structural general formula II, wherein Y is carbon or oxygen and X is oxygen or sulfur; or the compound has the chemical structural general formula III, wherein Y is hydrogen or halogen and X is oxygen or sulfur; or the compound has the chemical structural general formula IV, wherein Y is hydrogen or halogen. The compound is prepared by reacting substituted aniline with methyl trifluoropyruvate or ethyl trifluoropyruvate in a microwave reactor. The trifluoromethyl-containing indole ketone compound has anti-HIV reverse transcriptase activity, basically has no toxicity on cells, is expected to serve as an HIV reverse transcriptase inhibitor, and has important value on research of the HIV reverse transcriptase inhibitor. |
| priorityDate | 2011-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 120.