http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102671214-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49790ed5b8ddc5fa27a1d47732c612df |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 |
| filingDate | 2012-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_627bb6b666c235b4cc3ca71bc2ed17b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8724d28deb7ea1c27b0dfb85279eb398 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14d4138a2c14d42086faf45166e98729 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e89696ba152d87345e75963e1f23ffa8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_374b17c3e7b6cc2a0e3e596c12f6b541 |
| publicationDate | 2013-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102671214-B |
| titleOfInvention | Camptothecin supramolecular micelle prodrug for reducing, degrading and releasing drugs and preparation method and application |
| abstract | The invention discloses a camptothecin supramolecular micelle prodrug for reducing, degrading and releasing drugs and preparation method and application, wherein a polymer nano micelle which can generate nanometer scale molecular self assembly in environment of human bodies, is about 100nm in particle size, is narrow in distribution range, can cycle in blood for long term, targets cancer tissues and can control release rate of drugs is synthesized by physically packing camptothecin through supramolecular micelles aiming at poor solubility of the camptothecin. The camptothecin supramolecular micelle prodrug for reducing, degrading and releasing drugs increases water solubility of the camptothecin, reduces toxic and side effects of the camptothecin in maximum, increases efficacy and bioavailability at the same time, and overcomes the defects that clinical therapeutic effect of the camptothecin is not ideal at present. |
| priorityDate | 2012-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.