Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bceed6bebc0cc13575ef9690aa72e1c0 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2012-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7552da908e445ee43a8527701a56793 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f76eb9fbf2fea5d1d37a889f21309c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8919c2acbe0dfb7b8f0dd0f87c687091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfc9dd93ee880989f5ad2974a7f17d07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25271ebb8fa28a4dd3bc1119efe4284e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc959f1c10f7f78775d81e25cf657136 |
publicationDate |
2014-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-102643819-B |
titleOfInvention |
ShRNA of Rab23 and ientiviral vector and applications thereof |
abstract |
The invention discloses an interference Rab23 gene of siRNA. The siRNA is hairpin RNA (ribonucleic acid) formed aiming to a target sequence of the Rab23 gene; the siRNA is double-strand siRNA, wherein one strand of nucleotide sequence is shown as SEQ. ID. NO.1 or SEQ. ID. NO.2; the expression of the Rab23 protein is positive correlation with the development of skin scale cancer and is especially related with invasion ability of the skin scale cancer; and the invasion ability of skin scale cancer cells is enabled to lowered by the expression of the interference Rab23 protein. The invention also discloses applications of interference shRNA of the Rab23 gene target sequence in preparing a skin scale cancer resisting drug. |
priorityDate |
2012-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |