http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102641246-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_21207c582701b3492b563f7bece0c122 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4748 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate | 2012-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5f5eed05f2fd1eaaef31c2bad162fdd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2fecf8e049d0077be0d77be4f43ec7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ceff2e851fbd4f60bc485e7435abaca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3af63ba0d97197e352bad6cb7590514a |
| publicationDate | 2014-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102641246-B |
| titleOfInvention | Anti-tumor double-drug nano drug carrying microsphere and preparation method thereof |
| abstract | The invention relates to an anti-tumor drug, in particular to an anti-tumor double-drug nano drug carrying microsphere and a preparation method thereof. The double-drug nano drug carrying microsphere disclosed by the invention is formed by mixing paclitaxel (Ptx), concordant remedies and drug carrying materials, wherein the concordant remedies are tetrandrine (Tet), or curcumin (Cum) or resveratrol (Res), the drug carrying material is amphiphilic block copolymer, namely polycaprolactone-polyethylene glycol (mPEG-PCL) or polylactic acid-polyethylene glycol (mPEG-PLA) or polyglycolic acid-polyethylene glycol (mPEG-PLGA), synthesized by polycaprolactone or polylactic acid or polyglycolic acid and polyethylene glycol. The preparation method disclosed by the invention comprises the steps of dosage, medicine dissolving, dilution, purification, filtering, drying or freeze drying and the like to obtain the anti-tumor double-drug nano drug carrying microsphere or finished freeze-drying product. According to the anti-tumor double-drug nano drug carrying microsphere and the preparation method thereof, the concordant remedies have the synergistic effect of reinforcing the tumor inhibiting capability of the paclitaxel so as to improve the pesticide effect of the double drugs for resisting tumor in a synergy manner. |
| priorityDate | 2012-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.