http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102633739-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-26 |
| filingDate | 2012-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d64c94b01f3d983c0609a5c3e4c25a78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b199b135ff836c6519e2502a4358e89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c46f05cfdd9f2d44c257f88e5a8a3e84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5588fa1f4ce5da746832599e1ef3271d |
| publicationDate | 2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102633739-B |
| titleOfInvention | Method for synthesizing 2-(2-chlorophenyl)-4-(4-fluorophenyl)-5-[4-(mesyl) phenyl] thiazole |
| abstract | The invention discloses a method for synthesizing 2-(2-chlorophenyl)-4-(4-fluorophenyl)-5-[4-(mesyl) phenyl] thiazole. The method includes: thioanisole is reacted with acetyl chloride to generate 4-methylthio acetophenone which is reacted with 4-methyl fluorobenzoate to generate 1-(4-fluorophenyl)-3-(4-methylthio benzene)-1,3 diketone which is reacted with tert-butyl nitrite to generate 1-(4-fluorophenyl)-2-(4-methylthio benzene)-1,2 diketone which is reacted with 2-chlorobenzaldehyde to generate 2-(2-chlorophenyl)-4-(4-fluorophenyl)-5-[4-(methylthio) phenyl]thiazole which is oxidized to generate 2-(2-chlorophenyl)-4-(4-fluorophenyl)-5-[4-(mesyl) phenyl] thiazole. The method avoids usage of nitrine reagent and has important application value. |
| priorityDate | 2012-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.