| abstract |
A conjugate, or a pharmaceutically acceptable salt thereof, comprising a cyclosporine moiety of formula (I) linked to one or more mitochondrial targeting groups: wherein: A represents or, B represents methyl or ethyl, one of R and R * represents hydrogen and the other represents methyl , R represents ethyl or isopropyl, R represents hydrogen or methyl, and R represents -CH CH( CH3 ) CH3 , -CH2CH ( CH3 ) CH2CH3 , -CH( CH3 ) CH3 , or -CH( CH3 ) CH2CH3 . |