| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e2ba784a11bf94f0d7af0b295a8c05 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-64 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
2011-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1af97384c9abcf9544586e3e4841a052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f1889c62b205f140ebed109e66d5605
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_489c8c34b5c21a500bd6418022c10ca4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64f85aec12846690ecf89a9cf3c9da3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8edea921c3678bccc01b82900e870c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dc6eca9aefbf26f1fac29c39f3df724 |
| publicationDate |
2014-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-102618604-B |
| titleOfInvention |
Preparation method of cyclic lipopeptide compound |
| abstract |
The invention discloses a fermentation medium which comprises 0.5-5.0 wt% of amino acid or its derivative, 0.5-3.0 wt% of hard-soluble organic nitrogen source, and 1.0-10.0 wt% of carbon source. By using the medium of the invention to carry out biologic fermentation of the compound of formula I, the fermentation level can stably reach more than 0.5g/L, with the highest fermentation level being 1.0g/L. By using the strain mutagenized with Coleophoma empetri F-11899 (FERM BP2635), the fermentation level can even reach 1.5 g/L. Because the fermentation level is high and the amount of organic solvent used in the post-treatment is relatively reduced, the production cost is reduced, and the invention has high economic value and meets the need of industrial production. |
| priorityDate |
2011-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |