Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eda37409f26cb8e833ba67f2b1bc1fd5 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2012-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4bbd1ed657c0ce6353877c9459a6952 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbd874bf16a06b37ee1607374a4d0443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22d7e78ddb0e58e019aa31f24e15b8b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b81ae63b2ea7dc4cb5724eadeb0319b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30f001c72eeebf8df7887e02b13eb3d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_576c7963ea4cb56ad9d2fedde8160acd |
publicationDate |
2012-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-102617564-A |
titleOfInvention |
A kind of compound and preparation method thereof |
abstract |
The invention discloses a 2-substituted imino-3-substituted-5-[4-[2-[N-methyl-N-(2-pyridyl)]amino]ethoxy]benzylidene Base-thiazolidine-4-one derivatives and preparation method thereof, the compound has the functional group of thiazolidine-2,4-dione, and is chemically similar to thiazolidine-2,4-dione class of ketones very similar. The compound is based on 2-substituted imino-3-substituted-thiazolidin-4-one derivatives and 4-[2-[N-methyl-N-(2-pyridyl)]amino]ethoxybenzene Synthesized from formaldehyde. The results of preliminary screening experiments on the biological activity of all target compounds at the molecular level of PTP1B enzymes showed that some new compounds showed certain inhibitory activity on PTP1B. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104418811-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104059060-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104418811-B |
priorityDate |
2012-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |