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filingDate 2012-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4bbd1ed657c0ce6353877c9459a6952
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publicationDate 2012-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102617564-A
titleOfInvention A kind of compound and preparation method thereof
abstract The invention discloses a 2-substituted imino-3-substituted-5-[4-[2-[N-methyl-N-(2-pyridyl)]amino]ethoxy]benzylidene Base-thiazolidine-4-one derivatives and preparation method thereof, the compound has the functional group of thiazolidine-2,4-dione, and is chemically similar to thiazolidine-2,4-dione class of ketones very similar. The compound is based on 2-substituted imino-3-substituted-thiazolidin-4-one derivatives and 4-[2-[N-methyl-N-(2-pyridyl)]amino]ethoxybenzene Synthesized from formaldehyde. The results of preliminary screening experiments on the biological activity of all target compounds at the molecular level of PTP1B enzymes showed that some new compounds showed certain inhibitory activity on PTP1B.
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