http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102617433-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f501696709cd53f16cec9fbe026c284
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-12
filingDate 2012-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c81356376b6ec63ffb79759c29f459f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3aafb8ca970bcec93b3845f544f3e58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bea7efaaed61667aabb3e16da6100418
publicationDate 2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102617433-B
titleOfInvention Method for preparing (2S, 4R)-1-paranitro carbobenzoxy-4-methylsulfonyl pyrrolidine-2-methanol
abstract The invention provides a method for preparing (2S, 4R)-1-paranitro carbobenzoxy-4-methylsulfonyl pyrrolidine-2-methanol by four steps. The technological operation steps are simplified, technological continuity is higher, an intermediate does not need to be refined, industrial production is easily realized, production cost is reduced, types and consumption of organic solvents are greatly decreased, the single solvent is conveniently recycled and reused, and the novel technology is more environment-friendly. By the aid of the method, higher yield can be achieved, compound I hydroxyproline serves as a standard, total molar yield is higher than or equal to 75%, and final product purity is higher than or equal to 98.0%.
priorityDate 2012-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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