http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102608103-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65
filingDate 2012-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7857d20ad7415454e53b94552c173739
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publicationDate 2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102608103-B
titleOfInvention Surface enhanced Raman scattering (SERS) substrate and preparation method thereof
abstract The invention provides a surface enhanced Raman scattering (SERS) substrate and a preparation method thereof. The SERS substrate comprises a silicon substrate and a chemical modification layer arranged on the silicon substrate. The chemical modification layer includes a hydrophilic silane compound layer with area smaller than 7.5 square millimeter; a hydrophobic silane compound layer surrounding the hydrophilic silane compound layer; and a mono-layer metal nanoparticle layer arranged on the hydrophilic silane compound layer. Under action of the hydrophilic silane compound layer and the hydrophobic silane compound layer, aqueous solution of to-be-detected substance is concentrated on the middle small-area hydrophilic silane compound layer, to improve concentration degree of aqueous solution of the to-be-detected substance. The metal nanoparticle layer realizes more uniform distribution of aqueous solution of the to-be-detected substance. Therefore, the SERS substrate can improve signal intensity and detection sensitivity.
priorityDate 2012-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 47.