http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102604637-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-85 |
| filingDate | 2012-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102604637-B |
| titleOfInvention | The preparation method of the rear-earth-doped inorganic fluorescent nano-particle of biotin modification |
| abstract | The preparation method of the rear-earth-doped inorganic fluorescent nano-particle of a kind of biotin modification of disclosure.Utilize BTA-N, N, N ', N '-tetramethylurea hexafluorophosphoric acid ester (HBTU) and DIPEA (DIEA) are activator, at anhydrous N, in the solvent of dinethylformamide, the carboxyl of biotin being activated, then reacting formation amido link with the amino of nano-particle, thus realizing the biotin modification of rear-earth-doped inorganic fluorescent nano grain surface.Adopt biotin modification rear-earth-doped inorganic fluorescent nano-particle prepared by this method can carry out rapid and stable connection with Avidin, simultaneously because this connection can be carried out sensitive response by the specific luminescence of rare earth ion of doping in nano-particle, it was shown that the Application of micron obtained by this preparation method is in the potentiality of biomarker and immunoassay field. |
| priorityDate | 2012-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.