http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102604032-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc4e13141d402ceb885f368dfa042348
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G18-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G18-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G18-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G18-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L75-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
filingDate 2012-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9727bfcfda24ac5517883fd2e8603d01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3de07cb65300cde9b0051647c9e21977
publicationDate 2013-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102604032-B
titleOfInvention Thermo-sensitive chain extender and polyurethane hydrogel with double sensitivity of temperature and pH
abstract The invention discloses a thermo-sensitive chain extender and polyurethane hydrogel with double sensitivity of temperature and pH. The hydrogel is prepared by the following methods: mixing 15-20.6 percent of polyethylene glycol, 6.7-9.2 percent of polyhydric carboxylic acid, 25.2-34.6 percent of multi-isocyanate and dibutyltin dilaurate used as a catalyst to perform pre-condensation polymerization reaction; adding organic solvent to stop reaction to obtain a pre-polymer; adding 15.3-36.5 percent of a thermo-sensitive chain extender to perform chain extension reaction; adding 3.1-4.3 percent of polyhydric alcohol amine stop end after the pre-polymer is subjected to the chain extension; and then, adding 11.6-19.4 percent of a curing crosslinking agent to perform crosslinking reaction to obtain polyurethane hydrogel with double sensitivity of temperature and pH. The thermo-sensitive chain extender is prepared by the method, and a method for introducing the thermo-sensitive chain extender in polyurethane is provided, and the softness and hardness of the material are controlled in a post-crosslinking mode, so that the defects that introduction of groups and cross-linking solidity are carried out at the same time in the conventional way of excitation of double bonds are overcame, and the polyurethane hydrogel with double sensitivity of temperature and pH is prepared.
priorityDate 2012-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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