http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102603897-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2011-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102603897-B |
| titleOfInvention | Fusion protein containing guide peptide and GnRH-PE39KDEL as well as nucleic acid and application thereof |
| abstract | The invention discloses a novel fusion protein. A peptide segment (preferably a protein transduction domain (PTD)) is introduced, so as to improve the cell killing activity of an immunotoxin human leuterinizing hormone releasing hormone-Pseudomonas aeruginosa exotoxin A derivative (GnRH-PE39KDEL), and the peptide segment is positioned on the C-terminal of the human leuteinizing hormone releasing hormone (GnRH) and the N-terminal of the Pseudomonas aeruginosa exotoxin A derivative (PE39KDEL) to form the novel fusion protein together with the GnRH and PE39KDEL. The invention also relates to a nucleotide sequence for coding the fusion protein, an expression vector containing the nucleotide sequence, a host cell containing the expression vector and an application of the novel fusion protein used as an immunotoxin in an anti-cancer medicine. |
| priorityDate | 2011-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 338.