http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102603844-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6870d8e4b259747871e8dd476531c92 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 |
filingDate | 2012-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_762af8cbe40819ad0eeee4015dedef31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5f89e8e331d20165cb41c168a425f8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d37a4d147c18305f4c16a44ae79744d5 |
publicationDate | 2014-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102603844-B |
titleOfInvention | Preparation method of betamethasone intermediate |
abstract | The invention relates to a preparation process of a betamethasone intermediate. The structural formula of the betamethasone intermediate is shown as a formula I, and is prepared by undergoing a ketone group protection reaction, a Grignard reaction and a hydrolysis deprotection reaction on a compound III; and the ketone group protection reaction comprises making a compound II, diazanyl carboxylic ether and an acid react to obtain a compound IV. The method has high yield, and contributes to protecting the environment; and the use of toxic substances is avoided. The structural formula of the compound III is shown as a formula III. |
priorityDate | 2012-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.