| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f1130e23cff1328c0ae14101d12103f |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-60 |
| filingDate |
2012-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbb1ec9efc1538c3016f2ec837c6d82c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d72eb287994e42557f21a0c73ab5a995
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff0a45f803dcd71d96d040b443f5c659 |
| publicationDate |
2012-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-102603647-A |
| titleOfInvention |
18/19F-ester nitroimidazole compound and its preparation method and use as hypoxic tissue imaging agent |
| abstract |
The present invention relates to 18/19 F-ester nitroimidazole compound, its preparation method and its use as hypoxic tissue imaging agent. The present invention provides a class of F-ester nitroimidazole compounds represented by general formula 1, wherein the 18 F-ester nitroimidazole compound is a radioactive compound. Animal experiments on S180 tumor-bearing mice showed that the above 18 F-ester Nitroimidazole-like compounds have good tumor-targeted uptake and low liver background, and are potential PET hypoxia imaging agents. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109438517-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113501789-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3684781-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109438517-A |
| priorityDate |
2012-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |