http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102603613-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9de062d126f1ceb6ddf5c5be548c2ea |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4468 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P23-00 |
filingDate | 2012-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c983c3dd59c1752879cf3ef286ece4f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b371fc0a39f97a05136b60434c6bb66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34c996d0da7a0a42e82f3ea8efce08f0 |
publicationDate | 2012-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102603613-A |
titleOfInvention | 4-(methoxycarbonyl)-4-(N-phenylpropanylamino)-piperidine-1-substituted compound, preparation method and pharmaceutical use |
abstract | 4-(methoxycarbonyl)-4-(N-phenylpropanylamino)-piperidine-1-substituted compound, preparation method and pharmaceutical use. The structure of the compound is the free base in the form of formula (I) or the corresponding hydrochloride (I'), where n=0~3 integer, R is a sulfonyl group or a substituent with the core structure of propofol . The compound has good water solubility and stability, can have analgesic and sedative effects at the same time, is suitable for analgesic and sedative for patients under postoperative monitoring, and is especially beneficial to realize the operation of the patient's self-controlled drug delivery system, and can reduce anesthesia. Doctor's operation. The basic method for preparing the compound is to condense a compound having the core structure of remifentanil and a compound having the core structure of the corresponding substituent according to the properties of the substituent R. 4-(Methoxycarbonyl)-4-(N-phenylpropanylamido)-piperidine-1-substituted compound. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105753701-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105753701-A |
priorityDate | 2012-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.