| abstract |
The present invention relates to compound (I), wherein: means pyridazine, pyrimidine or pyrazine group, R independently represents a hydrogen atom, a halogen atom or a group selected from the following: -CN group, hydroxyl group, -COOR group, (C 1 -C 3 ) fluoroalkyl group, (C 1 -C 3 ) fluoroalkoxy group, -NO 2 group, -NR 1 R 2 group, (C 1 -C 4 ) alkoxy group , phenoxy and (C 1 -C 3 ) alkyl optionally substituted by hydroxyl, n is 1, 2 or 3, n' is 1 or 2, R' is a hydrogen atom, a halogen atom Or a group selected from the group consisting of (C 1 -C 3 )alkyl, hydroxyl, -COOR 1 group, -NO 2 group, -NR 1 R 2 group, morpholino or morpholino group , N-methylpiperazinyl, (C 1 -C 3 ) fluoroalkyl, (C 1 -C 4 ) alkoxy and -CN groups, Z is N or C, Y is N or C, X is N or C, W is N or C, T is N or C, U is N or C, for use as an agent for preventing, inhibiting or treating pathological or non-pathological conditions associated with premature aging. Certain of the compounds described are novel and form part of the present invention. |