http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102590511-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
filingDate 2012-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3107219f65ea71030071500c5c660158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_313348838e1d0c9ccef1fe90d93e1db9
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publicationDate 2014-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102590511-B
titleOfInvention Tumor diagnosis reagent or kit based on detection of IGFBP-2 (insulin-like growth factor binding protein 2) autoantibody or combined detection of IGFBP-2 antoantibody and IGFBP-2, as well as application thereof
abstract The invention provides a tumor diagnosis reagent or kit based on detection of an IGFBP-2 (insulin-like growth factor binding protein 2) autoantibody or combined detection of the IGFBP-2 autoantibody IGFBP-2. The tumor diagnosis reagent or kit comprises a first reagent group capable of detecting the IGFBP-2 autoantibody in a detected sample, or a first reagent group capable of detecting the IGFBP-2 autoantibody in the detected sample and a second reagent group capable of detecting IGFBP-2 in the detected sample. The invention also provides application of IGFBP-2 autoantibody detection or combined detection of the IGFBP-2 autoantibody and the IGFBP-2 in preparing the tumor diagnosis reagent or kit. Detection of the IGFBP-2 autoantibody can be used for diagnosing early-phase tumor or high-grade adenoma with cancerization risk, in particular for diagnosing prometaphase glioma and high-grade colorectal polyp and/or colorectal neoplasms of I-II grades with cancerization risk; and the combined detection of the IGFBP-2 autoantibody and the IGFBP-2 can be used for diagnosing tumors of different grades and monitoring each phase of a tumor from low grade to high grade, such as diagnosing and identifying astrocytoma, anaplastic astrocytoma and/or spongioblastoma, as well as I-IV grades of colorectal neoplasms.
priorityDate 2012-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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