http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102584917-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52b1c0c2d8e360eea2c314adcaac2b48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-07 |
| filingDate | 2011-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11de7e90c4f65ee1243ff49fb3ec5e33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb3e44a485e4ee7948df9746640044d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a529f33b9b218d7220a86028debcc2ca |
| publicationDate | 2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102584917-B |
| titleOfInvention | Preparation method of high-purity scutellarin crude drug |
| abstract | The invention relates to a preparation technology of a high-purity crude drug in pharmaceutics. The preparation technology comprises the steps of firstly, adding water into a breviscapinun crude product with more than 85% of scutellarin sold in the market for wetting, adding basic amino acid water solution to prepare water solution which has the pH value being 7.5-9.0 and includes 10mg-150mg/ml of breviscapinun; secondly, centrifugally clearing and filtering, taking filtrate to a macroporous resin chromatographic column taking polyacrylate as a substrate; and thirdly, adding a converting agent organic acid into collecting liquid, reducing scutellarin salt into scutellarin, naturally settling, discharging supernatant liquor, drying to obtain the high-purity scutellarin crude drug with the purity being over 99%. According to the preparation technology, as the organic solvent is not needed for recrystallization, the technology is continuous, automatic and large-scale; and more importantly, the organic solvents easy to burn and explode are avoided, and the high-purity scutellarin crude drug prepared by the preparation technology conforms to the industry policy of the national safety production. |
| priorityDate | 2011-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.