http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102584835-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65682d3e437c225d79b93953b4b26392 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-20 |
| filingDate | 2011-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1aad93c0058f3d762044391700e12728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a69e3b7512cdfb987b18d0e8899d7be |
| publicationDate | 2014-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102584835-B |
| titleOfInvention | Spiral heterocyclic compound containing indole structure and method for preparing same |
| abstract | The invention relates to the field of pharmaceutical chemistry, and discloses a spiral heterocyclic compound containing an indole structure and a method for preparing the same. The compound is 3'-amino spiro [indoline-3,1'-pyrazolo [1,2-b] phthalazine]-2,5'10'-triketones compound in a formula I, wherein R1 is -H or-CH3, R2 is -H, -CH3, -F, -Cl or-Br, X is -CN or -CO2C2H5. The method for preparing the spiral heterocyclic compound comprises the steps: malononitrile or ethyl cyanoacetate, isatin compound and phthalylhydrazine are dissolved in solvent, organic base or inorganic base is taken as catalyst, under the action of ultrasonic wave, the compound in the formula I is generated after the reaction. The compound is the spiral heterocyclic compound which contains the indole structure and has stable properties, the method for preparing the spiral heterocyclic compound takes short reaction time, requires simple reaction conditions, and can be completed after reaction for 0.5-2 hours under normal temperature, meanwhile, the yield of the reaction end products is high, and the aftertreatment is simple. |
| priorityDate | 2011-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.