http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102584715-A

Outgoing Links

Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-22
filingDate 2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_001674b6d2e576b4e1672e2c0881a92a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bf44caf9b486efdaecb789068211162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_627a47516982b909b4b7e223e5d2a551
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33ae3613f880cc4e4e1f47617ed7b30a
publicationDate 2012-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102584715-A
titleOfInvention Method for Synthesizing Optically Active Dihydropyrimidinethioketone Derivatives Catalyzed by Chiral Spirocyclic Phosphoric Acids
abstract The invention discloses a method for synthesizing dihydropyrimidinethioketone derivatives catalyzed by chiral spirocyclic phosphoric acid. It uses aldehyde, thiourea and acetoacetate as raw materials, with chiral spirocyclic phosphoric acid as catalyst, reacts at 20-90 o C for 24-72 hours in an organic solvent, under the protection of nitrogen, and purifies by column chromatography The separation process yields dihydropyrimidinethioketone derivatives. The invention has mild reaction conditions, simple process and convenient operation; the obtained dihydropyrimidine thioketone derivative has potential good biological activity and can be used as an intermediate for drug synthesis.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109134330-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103420921-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103159683-A
priorityDate 2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Predicate Subject
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID465649751
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID465485715

Total number of triples: 19.