http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102584715-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-22 |
filingDate | 2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_001674b6d2e576b4e1672e2c0881a92a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bf44caf9b486efdaecb789068211162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_627a47516982b909b4b7e223e5d2a551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33ae3613f880cc4e4e1f47617ed7b30a |
publicationDate | 2012-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102584715-A |
titleOfInvention | Method for Synthesizing Optically Active Dihydropyrimidinethioketone Derivatives Catalyzed by Chiral Spirocyclic Phosphoric Acids |
abstract | The invention discloses a method for synthesizing dihydropyrimidinethioketone derivatives catalyzed by chiral spirocyclic phosphoric acid. It uses aldehyde, thiourea and acetoacetate as raw materials, with chiral spirocyclic phosphoric acid as catalyst, reacts at 20-90 o C for 24-72 hours in an organic solvent, under the protection of nitrogen, and purifies by column chromatography The separation process yields dihydropyrimidinethioketone derivatives. The invention has mild reaction conditions, simple process and convenient operation; the obtained dihydropyrimidine thioketone derivative has potential good biological activity and can be used as an intermediate for drug synthesis. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109134330-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103420921-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103159683-A |
priorityDate | 2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID465649751 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID465485715 |
Total number of triples: 19.