http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102579407-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae1ffe37c5b16e0b0579825b48c1ca66 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 |
filingDate | 2012-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb94c1cfc3c8ae52435e7566f216d84b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d713271de71ee549c3a027694c853477 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f1ddd4f1299d4d4504f732d2b3a70c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20bd58d034790238d57405571f8439df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4344ee590cc772e655dc013206049f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7baad162109d3b648f24e87704ebe0f1 |
publicationDate | 2013-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102579407-B |
titleOfInvention | Preparation method for indapamide microsphere sustained release capsules |
abstract | Provided is a preparation method for indapamide microsphere sustained release capsules. The indapamide microsphere sustained release capsules, especially contents, are formed by microsphere of gastrointestinal tract release medicine manufactured by indapamide and high polymer materials with high potential of hydrogen (pH) dependency. The high polymer materials comprise polyacrylate E-100, hydroxypropyl methylcellulose phthalic ester HP-55 and hydroxypropyl methylcellulose succinate HAS which are respectively manufactured into stomach dissolving microsphere, intestines dissolving microshpere and colon dissolving microsphere with the indapamide. All microspheres are combined into particle dispersing capsules according to weight parts. After taken, medicine is released in the stomach and intestines according to pH gradient, blood concentration is stable, sustained release is achieved, medicine in the microsphere is highly dispersed and dissolved out to be completely absorbed, and biological utilization of oral medicine is improved. The medicine microsphere is simple in the preparation method and equipment and suitable for industrialization. |
priorityDate | 2012-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.