Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0eb3c391d7e38c89f330236184317fc |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70539 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91188 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-916 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-42 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2010-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b2fa7cdc612cd7f68f305e57438267b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6aece18d2403eeccb461c653c3a12f9e |
publicationDate |
2014-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-102576015-B |
titleOfInvention |
Serum markers predicting clinical response to anti-TNF[alpha] antibodies in patients with psoriatic arthritis |
abstract |
The invention provides tools for management of patients diagnosed with psoriatic arthritis, specifically, prior to the initiation of therapy with an anti-TNF [alpha] agent. The tools are specific markers and algorithms of predicting response to therapy based on standard clinical primary and secondary endpoints using serum marker concentrations. In one embodiment the baseline levels of VEGF, prostatic acid phosphatase, and adiponectin are used to predict the response at Week 14 after the initiation of therapy. In another embodiment, the change in a serum protein biomarker after 4 weeks of therapy is used such as MDC, lipoprotein a, and [beta] 2-microglobulin. |
priorityDate |
2009-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |