| abstract |
The present invention relates to a kind of pharmaceutical composition, it comprises the combination of following component: 1 benzyl 3 methylol indazole derivative, selected from ACE inhibitor, renin inhibitor, the depressor of ARB and CCB, and/or the pravastatin selected from Statins derivant.Described combination shows additive activity and synergistic activity at the reduction horizontal aspect of MCP 1, thus significantly improves inflammatory response suppression, and thus reduces the complication occurred in the patient suffer inflammatory diseases. |