http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102559852-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3d4964b5a4fef7e756d169c4a0b9c75 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2010-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27cd769b6c43f11d1b233c1f38a7656b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02d09f20d5071b0b987d57224f38245f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1299c8d600bfc237fbb8c8e47fe92860 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e312af2820a0de84c1008fed39acd17 |
publicationDate | 2014-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102559852-B |
titleOfInvention | Specific primes and liquid phase chip for AGT (angiotensinogen) and ACE (angiotensin-converting enzyme) gene polymorphism detection |
abstract | The invention discloses specific primes and a liquid phase chip for AGT (angiotensinogen) and ACE (angiotensin-converting enzyme) gene polymorphism detection. The liquid phase chip mainly contains ASPE (allele specific primer extension) which consists of tag sequences at 5' end and specific primers at 3'-end relative to a target gene mutation, wherein the specific primers respectively are SEQ ID NO. 9 and SEQ ID NO. 10, SEQ ID NO. 11 and SEQ ID NO. 12, SEQ ID NO. 13 and SEQ ID NO. 14 regarding to relative to the AGT gene, and/or SEQ ID NO. 15 and SEQ ID NO. 16 relative to the ACE gene; microspheres coated with anti-tag sequences; and amplification primers. The conformation between the detection result of the AGT and ACE gene polymorphism detection liquid phase chip and the result of a sequencing method is up to 100%. The prepared liquid phrase has excellent signal-noise ratio and can avoid cross reaction and realize the parallel detection of multiple polymorphic sites. |
priorityDate | 2010-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.