http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102558546-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02eada17c5cafccdaa5be25ff0e84fbc |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-48 |
filingDate | 2010-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55fd987a1e16727a518cd8d53e1e2e8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9c15b2f528244fc8c134f5f79eb58c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60e939d004d500be3fab654774f21f5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62aba4869547f9f913b5b290b65cbcb8 |
publicationDate | 2014-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102558546-B |
titleOfInvention | Polyethylene glycol glycyrrhetinic acid ester, composite drug-loaded micelle and preparation method and application thereof |
abstract | The invention belongs to the medicine field and particularly relates to a polyethylene glycol glycyrrhetinic acid ester, a composite drug-loaded micelle and a preparation method and an application thereof. The polyethylene glycol glycyrrhetinic acid ester, the composite drug-loaded micelle and the preparation method and the application thereof provide a compound--polyethylene glycol glycyrrhetinic acid ester which is prepared by glycyrrhetinic acid serving as a main raw material. Particularly, the compound is obtained by coupling of a hydroxyl or a carboxyl of the glycyrrhetinic acid with the polyethylene glycol or polyethylene glycol monomethyl ether. According to the test, the composite drug-loaded micelle which is prepared by mixing of the polyethylene glycol glycyrrhetinic acid ester with drugs has a small grain diameter and high encapsulated efficiency and drug loading capacity, provides a novel medicinal carrier for clinic, and is applicable to preparing drug-loaded micelles. |
priorityDate | 2010-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.