Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-62 |
filingDate |
2011-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67f7ac81583d1151a4b60c454112de66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d11681ad6631ff60b3cc2243b10b37c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4139856da1de079100457651635f1b64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_067e1f7ae41e5de463933644f3a5328a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a165d1501ae5efa0dd38934adc2379b |
publicationDate |
2014-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-102558307-B |
titleOfInvention |
Octapeptin as well as preparation and application thereof |
abstract |
The invention provides a new octapeptin having biological control and medical treatment application potential values as well as a preparation method and an application thereof. The structure of the octapeptin is as shown in a formula (I). The new octapeptin provided by the invention has the beneficial effects that the octapeptin which has toxicity being less than that of polymyxin B and has medical treatment application value as well as the preparation method and application thereof are provided; an in vitro experiment indicates that the compound has obvious inhibition effects on tested Gran-negative bacteria; and an animal experiment indicates that the compound has a good treatment effect on a mouse septicemia model caused by Escherichia coli. |
priorityDate |
2011-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |