| abstract |
The invention discloses a novel thiazolidine derivant and a preparation method, a medicine combination and a purpose thereof, which specifically relate to the thiazolidine derivant shown as the formula I and the formula II, officinal salt of the derivant, a precursor or a derivant with the same biological function with the thiazolidine derivant, the preparation method of the thiazolidine derivant, the combination of one or a plurality of thiazolidine derivants and the purpose of the compound in treatment on diseases related with glucokinase and a peroxisome proliferators activated receptor, such as diabetes mellitus and obesity. |